True/False
Indicate whether the
sentence or statement is true or false.
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1.
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The most frequently used positron emitting radionuclides for PET Imaging include
Oxygen-13, Nitrogen-15, Carbon-11, and Fluorine 18.
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2.
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The most frequently used 18-F labeled radiopharmaceutical is 2-deoxy-2 (F-18)
fluoro-D-glucose (FDG).
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3.
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The mechanism of F-18 (FDG) trapping follows the glucose biochemical
pathways.
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4.
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F-18 (F-Dopa) can cross-over the Blood Brain Barrier (BBB).
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5.
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Oxygen-15 Carbon Monoxide binds to hemoglobin in the RBCs and allows the study
of RBC volume.
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6.
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Oxygen -15 Water is the most versatile PET radionuclide.
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7.
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Carbon-11 Acetate can be used for myocardial metabolism or to evaluate prostate
carcinomas.
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8.
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Oxygen-15 Carbon Dioxide is administered to a patient via inhalation.
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Multiple Choice
Identify the
letter of the choice that best completes the statement or answers the question.
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9.
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Which radionuclide mimic biological glucose utilization?
a. | F-18 (FDG) | c. | F-18 (FLT) | b. | F-18 (F-Dopa) | d. | F-18 Chloride |
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10.
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Which radionuclide is upregulated in the Synthesis Phase of the cellular
mitotic cycle and is used in oncological applications for probing to measure cellular
proliferation?
a. | F-18 (F-Dopa) | c. | F-18 (FLT) | b. | F-18 (FDG) | d. | F-18 Chloride |
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11.
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Which of the following is not a FDA Approved indication for F-18 (FDG)?
a. | Myocardial Perfusion | c. | Lymphomas | b. | Breast Cancer | d. | Refractory
Seizures |
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12.
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Which PET radionuclide can be quantified and determine a patients risk for a
stroke?
a. | Oxygen -15 Water | c. | F-18 (FLT) | b. | F-18 (FDG) | d. | F-18 (F-Dopa) |
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Matching
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Match the following Maximum Positron Energy with their appropriate
radionuclide; a. | F-18 | d. | O-15 | b. | N-13 | e. | Cs-137 | c. | C-11 |
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13.
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662 KeV
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14.
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960 KeV
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15.
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640 KeV
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16.
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1.72 MeV
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17.
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1.19 MeV
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Match the following radionuclides with their appropriate half-lifes; a. | Oxygen-15 | d. | Fluorine-18 | b. | Carbon-11 | e. | Rubidium 82 Chloride | c. | Nitrogen-13 |
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18.
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10 minutes
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19.
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20 minutes
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20.
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110 minutes
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21.
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2.04 minutes
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22.
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76 seconds
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Match the following pathological diseases with their appropriate
radionuclides: a. | F-18 (FDG) | e. | F-18 Chloride | b. | Carbon 11
Acetate | f. | Oxygen-15
Water | c. | F-18 (F- Dopa) | g. | F-18 (FLT) | d. | Nitrogen 13
Ammonia |
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23.
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Lung Cancer
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24.
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Esophogeal Cancer
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25.
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Colorectal Cancer
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26.
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Head and Neck Cancer
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27.
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Thyroid Cancer
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28.
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Lymphomas
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29.
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Melanomas
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30.
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Refractory Seizures
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31.
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Myocardial Viability
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32.
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Breast Cancer
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33.
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Myocardial Metabolites
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34.
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Osteogenic Lesions
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35.
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Myocardial Perfusion
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36.
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Parkinsons Disease
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37.
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Cellular Proliferation of Thymididine
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Short Answer
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38.
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Which PET radionuclide is used to study the brain for Parkinsons Disease?
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39.
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Which PET radionuclide can be used for ruling out Hepatocellular
Carcinomas?
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40.
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What is the typical clinical application of Nitrogen-13 Ammonia?
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